Linkage disequilibrium and historical effective population size in the Thoroughbred horse
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چکیده
منابع مشابه
Linkage disequilibrium and effective population size when generations overlap
Estimates of effective population size are critical for species of conservation concern. Genetic datasets can be used to provide robust estimates of this important parameter. However, the methods used to obtain these estimates assume that generations are discrete. We used simulated data to assess the influences of overlapping generations on the estimates of effective size provided by the linkag...
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Effective population size (N(e)) determines the amount of genetic variation, genetic drift, and linkage disequilibrium (LD) in populations. Here, we present the first genome-wide estimates of human effective population size from LD data. Chromosome-specific effective population size was estimated for all autosomes and the X chromosome from estimated LD between SNP pairs <100 kb apart. We accoun...
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Characterisation of linkage disequilibrium and subsequent estimation of effective population size in Thoroughbred horses using single nucleotide polymorphism markers L J Corbin, S C Bishop, J E Swinburne, M Vaudin, S C Blott, J A Woolliams The Roslin Institute and Royal (Dick) School of Veterinary Studies, University of Edinburgh, Edinburgh, United Kingdom, Animal Health Trust, Newmarket, Unite...
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The Lundehund is an old dog breed with remarkable anatomical features including polydactyly in all four limbs and extraordinary flexibility of the spine. We genotyped 28 Lundehund using the canine Illumina high density beadchip to estimate the effective population size (Ne) and inbreeding coefficients as well as to identify potential regions of positive selection. The decay of linkage disequili...
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Effective population size (Ne) is an important genetic parameter because of its relationship to loss of genetic variation, increases in inbreeding, accumulation of mutations, and effectiveness of selection. Like most other genetic approaches that estimate contemporary Ne, the method based on linkage disequilibrium (LD) assumes a closed population and (in the most common applications) randomly r...
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ژورنال
عنوان ژورنال: Animal Genetics
سال: 2010
ISSN: 0268-9146
DOI: 10.1111/j.1365-2052.2010.02092.x